While I was creating my first react app, I faced the following problem... Error: EPERM: operation not permitted, mkdir 'C:\Users\Vighnesh' Actually, in my current laptop, my username has a space in between "Vighnesh Bendre". Hence, when I run following command, I get the error. C:\Users\Vighnesh Bendre\github-finder> npx create-react-app . The best solution I found was here . It goes like this... Step 1. Run "npm config edit". This will open a notepad with commented text, 2. Find "cache". Mine looked like this... ; cache=C:\Users\Vighnesh Bendre\AppData\Roaming\npm-cache 3. Change it to remove the space & shorter version of folder name. cache=C:\Users\VIGHNE~1\AppData\Roaming\npm-cache 4. If you want to know the shorter version of the folder name, then use "dir /x" in cmd prompt. 5. And dont forget to remove the ';', 6. Once you save & close this file, then run "npx create-react-app ....